G6PD Deficiency and Chronic Hemolysis: Four New Mutants—Relationships Between Clinical Syndrome and Enzyme Kinetics

G6PD deficiency and chronic hemolysis: four new mutants--relationships between clinical syndrome and enzyme kinetics.

G6PD deficiency of the common type (Gd’ and Gd11t.d1 rranenn) results in extremely mild chronic hemolysis. In contrast, 65 males (from 47 unrelated families) have been reported with a different syndrome of severe chronic hemolysis associated with a superficially similar deficiency in the activity of G6PD. Five new such patients (from four unrelated families) are reported. Biochemical characteri...

Can acetaminophen cause hemolysis in G6PD deficiency?

Methemoglobinemia and intravascular hemolysis in a patient with G6PD deficiency.

G6PD Enzyme Deficiency in Neonatal Pathologic Hyperbilirubinemia in Yazd

Abstract Background About 7.5% of the world population carries one or two deficient copy of glucose-6-phosphate dehydrogenase (G6PD) genes. According to WHO, its prevalence in Iran is 10 to 14.9%. This study aimed on determination of frequency of G6PD deficiency in neonates with jaundice who were hospitalized during 6 months (September 2008 to February 2009) in the city of Yazd, Iran. Materi...

Fava Bean Ingestion: the Most Important Risk Factor of Hemolysis in G6PD Deficiency in Iran

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most known enzyme defects in Iran with various genetic mutations. We aimed to study the predisposing factors of hemolysis in children with G6PD deficiency. Methods: This study was done during 2007-2012 in two referral centers of Mofid Children’s Hospital and Baqiyatallah Hospital, Tehran, Iran. The hospital rec...